Effects of BMI on Blood Pressure and Urinary Excretion of Sodium, Chloride and Potassium in Young Paraguayans

Tania Campagnoli, Lorena Gonzalez Stark, Maria de los Angeles Ojeda, Francisco Santacruz, Carlos Franco Palacios

Abstract


Background: Obesity has been associated with an increased risk for coronary disease, type 2 diabetes, hyperlipidemia and mortality. The demographics of Paraguay show that most of the population is of mixed European and Amerindian descent. Most of the studies performed in Hispanics, particularly in the United States fail to identify their country of origin. There is a paucity of data in Paraguay about the relationship between BMI and BP in young adults. Furthermore, there is an increased prevalence of overweight, obesity and hypertension in the country. In this study, we hypothesized that even early increments of BMI are associated with increased blood pressure (BP) readings in young adults in Paraguay. 

Methods: Cross-sectional study, performed in 72 adult participants, from Asuncion Paraguay. There is no similar study published in this country. BMI, BP readings and urinary excretion of Na, K and Cl were studied.

Results: Mean age 25.2 ± 1.52 years. Mean BMI 24.1 ± 3.66. There was a linear relationship between BMI and SBP, DBP, MAP and urine Na, K and Cl across all levels. A multivariate analysis, adjusting for gender, showed that increased BMI is associated with increased BP readings. A BMI of 23.4 was the best cut-off for a BP equal or higher than 135/85 mmHg (pre- hypertension), (AUC = 0.80). A BMI of 24.2 was the best cut off for a BP equal or higher than 140/90 (AUC = 0.80). After excluding participants with SBP equal or higher than 140 mmHg and DBP equal or higher than 90 mmHg, BMI was still associated with increased SBP and DBP even in normotensive individuals. After excluding obese and overweight patients, we found that even a small increase of BMI was associated with an increase in blood pressure.  

Conclusions: BMI values of 24.2 and 23.4 were associated with BP of 140/90 and 135/85 respectively. Since the BMI cut-off for obesity was established in different cohorts, we might need to create a more specific set of values for the Paraguayan population, as the values proposed by the American Heart Association are probably rather high for this population.




doi:10.4021/wjnu8e


Keywords


BMI; Hypertension; Paraguayan adults 

Full Text: HTML PDF
 
Home     |     Log In     |      About     |      Search     |      Current     |      Archives     |      Submit      |     Subscribe


 

     

Aims and Scope

Current Issues

Conflict of Interest

About Publisher

Editorial Board

Archives

Copyright

Company Profile

Editorial Office

Misconduct and Retraction

Permissions

Company Registration

Contact Us

Abstracting and Indexing

ICMJE

Ownership

Instructions to Authors

Access

Declaration of Helsinki

Contact Publisher

Submission Checklist

Reprints

Terms of Use

Company Address

Submit a Manuscript

Open Access Policy

Privacy Policy

Browse Journals

Publishing Fee

Publishing Policy

Disclaimer

Recent Highlights

Peer-Review Process

Publishing Quality

Code of Ethics

Advertising Policy

Manuscript Tracking

Advanced Search

For Librarians

Careers

Publishing Process

Publication Frequency

For Reviewers

Propose a New Journal

       
       

World Journal of Nephrology and Urology, quarterly, ISSN 1927-1239 (print), 1927-1247 (online), published by Elmer Press Inc.     
The content of this site is intended for health care professionals.
This is an open-access journal distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, which permits unrestricted
non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Creative Commons Attribution license (Attribution-NonCommercial 4.0 International CC-BY-NC 4.0)


This journal follows the International Committee of Medical Journal Editors (ICMJE) recommendations for manuscripts submitted to biomedical journals,
the Committee on Publication Ethics (COPE) guidelines, and the Principles of Transparency and Best Practice in Scholarly Publishing.

website: www.wjnu.org   editorial contact: editor@wjnu.org
Address: 9225 Leslie Street, Suite 201, Richmond Hill, Ontario, L4B 3H6, Canada
© Elmer Press Inc. All Rights Reserved.

DECLARATION: THIS JOURNAL SITE OUTLOOK IS DESIGNED BY THE PUBLISHER AND COPYRIGHT PROTECTED. DO NOT COPY!