Vesicoureteral Reflux Management With Subureteral Injection of Polydimethylsiloxane in Cases of Recurrent Pyelonephritis in Transplanted Kidneys

Arbey Aristizabal-Alzate, Guillermo Salazar-Villa, Carlos Yepes-Delgado, Lina Maria Serna-Higuita, John Fredy Nieto-Rios, Catalina Ocampo-Kohn, Carlos Uribe-Trujillo, Matilde Henao-Velasquez, Gustavo Zuluaga-Valencia

Abstract


Background: Kidney graft pyelonephritis is a common complication after renal transplantation, often prompted by vesicoureteral reflux (VUR). An effective and minimally invasive strategy for managing reflux that allows a decrease in the risk of recurrent pyelonephritis is desirable. The aim of this study was to describe our experience with an endoscopic treatment with subureteral injection of polydimethylsiloxane for the treatment of recurrent pyelonephritis of renal grafts secondary to VUR.

Methods: Between 2011 and 2016, 17 subureteral polydimethylsiloxane injection procedures were performed. Patient monitoring was done by outpatient consultation and medical record review. The number of pyelonephritis events before and after the procedure and its safety were compared.

Results: Forty-six infection episodes occurred before the procedure (2.71 infections/patient/year) and 10 infection episodes occurred after the procedure (0.59 infections/patient/year), representing a 78.3% reduction of infections/patient/year. The procedure was well tolerated and safe, with no resultant obstructive complications or changes in renal function and no long-distance migration of the bulking agent detected by monitoring.

Conclusion: Consistent endoscopic treatment with subureteral injection of the bulking agent polydimethylsiloxane to manage VUR in cases of recurrent pyelonephritis of kidney grafts is a non-invasive treatment option with a good success rate and safety profile.




World J Nephrol Urol. 2016;5(4):71-78
doi: https://doi.org/10.14740/wjnu296w

 


Keywords


Renal transplantation; Pyelonephritis; Urinary tract infection; Vesicoureteral reflux; Endoscopic treatment

Full Text: HTML PDF
 
Home     |     Log In     |      About     |      Search     |      Current     |      Archives     |      Submit      |     Subscribe


 

     

Aims and Scope

Current Issues

Conflict of Interest

About Publisher

Editorial Board

Archives

Copyright

Company Profile

Editorial Office

Misconduct and Retraction

Permissions

Company Registration

Contact Us

Abstracting and Indexing

ICMJE

Ownership

Instructions to Authors

Access

Declaration of Helsinki

Contact Publisher

Submission Checklist

Reprints

Terms of Use

Company Address

Submit a Manuscript

Open Access Policy

Privacy Policy

Browse Journals

Publishing Fee

Publishing Policy

Disclaimer

Recent Highlights

Peer-Review Process

Publishing Quality

Code of Ethics

Advertising Policy

Manuscript Tracking

Advanced Search

For Librarians

Careers

Publishing Process

Publication Frequency

For Reviewers

Propose a New Journal

       
       

World Journal of Nephrology and Urology, quarterly, ISSN 1927-1239 (print), 1927-1247 (online), published by Elmer Press Inc.     
The content of this site is intended for health care professionals.
This is an open-access journal distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License, which permits unrestricted
non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Creative Commons Attribution license (Attribution-NonCommercial 4.0 International CC-BY-NC 4.0)


This journal follows the International Committee of Medical Journal Editors (ICMJE) recommendations for manuscripts submitted to biomedical journals,
the Committee on Publication Ethics (COPE) guidelines, and the Principles of Transparency and Best Practice in Scholarly Publishing.

website: www.wjnu.org   editorial contact: editor@wjnu.org
Address: 9225 Leslie Street, Suite 201, Richmond Hill, Ontario, L4B 3H6, Canada
© Elmer Press Inc. All Rights Reserved.

DECLARATION: THIS JOURNAL SITE OUTLOOK IS DESIGNED BY THE PUBLISHER AND COPYRIGHT PROTECTED. DO NOT COPY!