World Journal of Nephrology and Urology, ISSN 1927-1239 print, 1927-1247 online, Open Access
Article copyright, the authors; Journal compilation copyright, World J Nephrol Urol and Elmer Press Inc
Journal website http://www.wjnu.org

Original Article

Volume 7, Number 1, March 2018, pages 25-31


Correlative Analysis Between Severity of Urolithiasis and Laboratory Parameters and Its Implication in Evaluation of the Probable Risk Profile

Tables

Table 1. Distribution Pattern of Categorical and Clinical Parameters With Overall Distribution
 
Age (years)Mean ± SD55.15 ± 14.26
GenderMale/female87/64
RecurrenceYes/no50/101
BMIMean ± SD25.21 ± 3.26
HTNPresent/absent48/103
DMPresent/absent29/122
CKDPresent/absent44/107
DM + CKDPresent/absent12/139
Stone multiplicityPresent/absent85/66
Upper tract stone site0/1/232/62/57
Upper tract obstruction side0/1/216/65/67
Large stone bulkPresent/absent41/110
Ipsilateral kidney damageMild/moderate/severe48/80/23

 

Table 2. Median Values of Continuous Variables With Corresponding P Values (Chi-Square Analysis/Pearson’s R Analysis)
 
VariableGroupP value
KidneyUreterKidney + UreterBladder
Age56.4258.1948.6152.090.034
BMI25.724.6524.6124.560.574
Serum urea5.666.015.95.870.95
Serum uric acid0.360.350.330.360.541
Serum creatinine93.5288.5169.4595.060.029
Serum ALP75.0876.3882.9264.670.067
Serum albumin42.6941.0741.7241.860.012
Serum Na144143.73143.131420.032
Serum K3.963.954.023.970.893
Serum Ca2.282.292.262.280.683
Serum Mg0.880.890.870.930.045
Serum PO41.161.081.161.130.339
Urine specific gravity1.0211.0191.0191.0220.587
Urine pH5.936.025.825.840.801

 

Table 3. Significant Association and Correlation Parameters of Categorical Variables and Clinical Parameter Groups
 
VariableChi square coefficientP valuePearson r coefficientP value
Gender7.280.063-0.0150.859
Recurrence4.7060.0193.080.042
HTN8.5280.0015.670.036
DM II5.6350.3020.010.907
CKD8.660.0437.420.027
DM + CKD2.920.404-0.0020.979
Multiple stones8.3480.039-4.090.027
Upper tract stone side14.7430.033-0.8580.041
Upper tract obstruction side14.810.0490.2690.022
Large stone bulk2.0720.5580.0210.798
Ipsilateral kidney damage14.270.0483.10.038

 

Table 4. Clinical Parameter Groups and Corresponding Biochemical and Epidemiological Variables With Corresponding Correlation Values
 
VariableMultiplicityStone sideIpsilateral kidney damageLarge stone bulkObstruction side
Pearson’s r valueP valuePearson’s r valueP valuePearson’s r valueP valuePearson’s r valueP valuePearson’s r valueP value
Gender-0.870.081-0.70.99-0.0810.560.2120.43-0.550.011
Age0.650.2392.320.024.550.0010.8790.0045.560.033
Recurrence0.6320.0018.060.0350.6320.0211.120.090.560.129
BMI0.590.2653.670.860.890.10.9740.1349.870.044
DM0.5610.4352.860.770.6610.1010.450.1720.360.067
CKD0.0620.0013.440.260.7620.0020.4410.0238.060.055
HTN0.980.7654.560.140.980.0011.020.560.670.113
Serum Na5.130.0030.870.870.1130.810.1670.870.860.088
Serum K5.920.964.360.660.2230.4480.0120.366.440.021
Urea8.340.575.060.240.4580.010.1830.260.970.954
Creatinine13.740.164.670.0020.8860.0010.3930.471.560.039
Serum ALP14.810.241.860.560.0930.3310.9480.860.870.113
Serum albumin1.0720.0621.440.970.0880.0010.110.449.360.121
Serum Ca14.270.853.970.260.0680.0980.8010.0025.060.001
Serum Mg0.1830.1125.560.090.290.1-0.6310.072-4.670.038
Serum PO40.2930.180.560.060.2430.2950.4010.0016.860.042
Specific gravity1.950.0951.870.040.4160.2330.1980.980.440.098
pH2.110.0880.360.0810.6650.3760.10.110.7750.1
Urine infection1.80.0018.060.0030.8850.4310.4420.6890.4430.01
Urine albumin2.630.0120.4450.9970.0050.9813.650.0110.0910.002